Sardar Azmoun opened Indias goal with a header in the 29th minute.
Iran captain Andranik Teymourian was on target, firing home a loose ball in the 47th minute.
Two minutes later, Mehdi Taremi scored from a decent range and made it 3-0 for Iran.
Carlos Queirozs men were dominant team but they squandered their chances.
The win took Iran to the top of group D with seven points while India remained at the bottom of the group with no points.
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By Tasnim News Agency