The former Israeli PM and president, Shimon Peres, has died aged 93.
He suffered a stroke two weeks ago and his condition improved before a sudden deterioration on Tuesday.
Mr Peres, who was one of the last of a generation of Israeli politicians present at the new nation's birth in 1948, served twice as the country's prime minister and once as president.
He won the Nobel Peace prize in 1994 for his role negotiating peace accords with the Palestinians a year earlier.
He once said the Palestinians were Israel's "closest neighbours" and might become its "closest friends".
Mr Peres died in a hospital near Tel Aviv early on Wednesday, with his family at his bedside.
He had been in the intensive care unit of the Sheba Medical Centre after suffering a major stroke on 13 September.
Israel's Prime Minister Benjamin Netanyahu expressed his "deep personal grief on the passing of the beloved of the nation".
Meanwhile US President Barack Obama called Mr Peres his "dear friend" in a statement, and said: "He was guided by a vision of the human dignity and progress that he knew people of goodwill could advance together."
Mr Peres shared his Nobel Peace Prize with Prime Minister Yitzhak Rabin, who was later assassinated, and Palestinian leader Yasser Arafat.
By BBC